Napissara Boonpraman, PhD
- Postdoctoral Researcher
- Sammi Lab
- Department of Translational Neuroscience
- College of Human Medicine, Michigan State University
Biography
Dr. Boonpraman is a postdoctoral researcher in the Department of Translational Neuroscience at Michigan State University’s College of Human Medicine, working in Dr. Shreesh Raj Sammi’s laboratory. She earned both her Bachelor’s degree and Master of Engineering in Chemical Engineering (Biopharmaceutical Engineering) from King Mongkut’s University of Technology Thonburi (KMUTT), Thailand. During her master’s research, conducted at Soonchunhyang University in South Korea, she explored heterologous gene expression for bioactive metabolite production.
Dr. Boonpraman received her Ph.D. in Medical Sciences (Neuroscience) from Soonchunhyang University in 2023, where her research focused on oxidative stress mechanisms in neurodegenerative disease models. Outside of the laboratory, she enjoys cooking, traveling, exploring new places, and spending time with her cats.
Education
|
Institution |
Field of Study |
Degree Earned |
Year |
|---|---|---|---|
|
King Mongkut’s University of Technology Thonburi (KMUTT), Thailand |
Chemical Engineering |
B.E. |
2014-2017 |
|
King Mongkut’s University of Technology Thonburi (KMUTT), Thailand |
Chemical Engineering (Biopharmaceutical Engineering) |
M.E. |
2017-2019 |
|
Soonchunhyang University, South Korea |
Medical Sciences |
PhD |
2020-2023 |
Research Interests
Dr. Boonpraman’s research focuses on how environmental toxicants such as per- and polyfluoroalkyl substances (PFAS) and organophosphate pesticides contribute to the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Her work investigates the mechanisms of mitochondrial dysfunction, oxidative stress, and neuroinflammation that underlie these disorders.
She employs a range of experimental models, including human induced pluripotent stem cell (iPSC)-derived neurons, blood–brain barrier (BBB) co-culture systems, rodents, and C. elegans, to uncover mechanistic pathways linking toxicant exposure to neuronal and vascular pathology.
Technical Expertise
- Cell culture
- iPSC-derived neuronal differentiation and maintenance
- Blood–brain barrier (BBB) co-culture and TEER measurements
- Mitochondrial enzyme activity and bioenergetic assays
- Microscopy and live-cell imaging
- Immunohistochemistry and immunofluorescence
- Immunoblotting
- Gene expression analysis (qPCR, RT-PCR)