Lindsey Sime earned her B.S. in Psychology with a minor in Biology from the University of Wisconsin-Eau Claire in 2010. She joined the Neuroscience graduate program at Michigan State University in 2022 and currently conducts her doctoral research under the mentorship of Dr. Marcia Gordon in the Department of Translational Neuroscience. Lindsey’s research investigates how microglial aging and estrogen loss influence Alzheimer’s disease pathology and neuroinflammation in mouse models of amyloid-enhanced tauopathy. Her work integrates molecular, histological, and behavioral approaches with AAV gene delivery and pharmacological modulation to identify therapeutic targets and biomarkers of neurodegeneration. Outside of the lab, Lindsey enjoys travel, running, equestrian sports, and spending time with her husband and their two cats.