September News

September 30, 2024

  • Congratulations to Dr. Ahlam Soliman on her successful defense!
  • Dr. Maggie Caulfield has accepted a new position at Parkinson’s Foundation as Director of Research Programs. Her last day at MSU was August 13.
  • Lucas Pozzo-Miller has accepted a secondary position within Translational Neuroscience.
  • Drs. Joe Patterson (PI) and Matt Benskey (Co-I) have been awarded $96,411.09 by the MJFF. “Assessment of the properties and seeding capacity of preformed fibrils generated from human and mouse α-syn monomer produced by Proteos Inc.” 9/1/2024 – 8/31/2026
  • Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease. Beckman D, Diniz GB, Ott S, Hobson B, Chaudhari AJ, Muller S, Chu Y, Takano A, Schwarz AJ, Yeh CL, McQuade P, Chakrabarty P, Kanaan NM, Quinton MS, Simen AA, Kordower JH, Morrison JH. Alzheimers Dement. 2024 Jun 21. doi: 10.1002/alz.13868. Online ahead of print. PMID: 39030748
  • Alzheimers Dement. 2024 Jul 30. doi: 10.1002/alz.14044. Online ahead of print. DOI: 10.1002/alz.14044 A functional aged human iPSC-cortical neuron model recapitulates Alzheimer's disease, senescence, and the response to therapeutics Leandro H Gallo, Nesar Akanda, Kaveena Autar, Aakash Patel, Ian Cox, Haley A Powell, Marcella Grillo, Natali Barakat, Dave Morgan, Xiufang Guo, James J Hickman Affiliations expand PMID: 39077965
  • Advancing age and the rs6265 BDNF SNP are permissive to graft-induced dyskinesias in parkinsonian rats. Mercado NM*, Szarowicz C*, Stancati JA, Sortwell CE, Boezwinkle SA, Collier TJ, Caulfield ME, Steece-Collier K. NPJ Parkinson's Dis. 2024 Aug 23;10(1):163. doi: 10.1038/s41531-024-00771-6. PMID: 39179609 *Co-first authors
  • Dr. Matt Benskey was awarded the Michigan ADRC Isadore and Margaret Mezey junior Investigator Conference Award to attend the 2024 Alzheimer’s Association International Conference.
  • Dr. Matt Benskey was awarded $314,000 from NIH/NIA. NIH R03: Investigating mechanisms of Complement Mediated Synaptic Removal. The goal of this application is to identify molecules that recruit complement C1q to Tau affected Synapses. 04/01/2024 – 03/31/2026.
  • Yamaguchi T, Hamano T, Sada K, Asano R, Kanaan NM, Sasaki H, Yen SH, Kitazaki Y, Endo Y, Enomoto S, Shirafuji N, Ikawa M, Yamamura O, Fujita Y, Aoki K, Naiki H, Morishima M, Saito Y, Murayama S, Nakamoto Y. Syk inhibitors reduce tau protein phosphorylation and oligomerization. Neurobiol Dis. 2024 Sep 2:106656. PMID: 39233131