Joseph Patterson, PhD

• Assistant Professor

• Department of Translational Neuroscience
• Michigan State University College of Human Medicine

• Grand Rapids Research Center
• 400 Monroe Ave NW, Grand Rapids, MI 49503
• patte401@msu.edu

Biography

Joseph Patterson received his Bachelor’s degree in biology with an emphasis in microscopy, and his Master’s degree in biology from Central Michigan University. He earned his Ph.D. in genetics from Michigan State University in the lab of Keith Lookingland and John Goudreau. In 2016, he started his postdoctoral training in the Lab of Caryl Sortwell in the Department of Translational Neuroscience at the Michigan State University College of Human Medicine campus in Grand Rapids. Currently he is studying features of Parkinson’s disease in a synucleinopathy model driven by the administration of preformed fibrils of alpha-synuclein.

• Dr. Patterson's bibliography (NEED)

Education

Research Interests

Dr. Patterson’s research focuses on the identification of the genetic signatures specific to the progression of synucleinopathies, such as Parkinson’s disease. An additional focus of his is the testing of potential disease modifying therapies in a synucleinopathy model that recapitulates key features of Parkinson’s disease.

Technical Expertise

• Immunohistochemistry
• Immunofluorescence
• Stereological analysis
• Stereotaxic Surgery (Rat and Mouse)
• Neurotoxicant Parkinsonian Rodent Models
• Synucleinopathy Rodent Model
• Synthesis of Preformed Fibrils of Alpha-Synuclein
• Electron Microscopy
• Laser Capture Microdissection
• DNA/RNA Isolation
• Droplet Digital PCR
• SDS-PAGE
• Western Blotting