Jeremy M. Van Raamsdonk, Ph.D.
Assitant Professor of Translational Science & Molecular Medicine
Department of Translational Science & Molecular Medicine
Mailing Address & Contact Information
Laboratory of Aging and Neurodegenerative Disease (LAND)
Center for Neurodegenerative Science, Van Andel Research Institute
333 Bostwick Avenue NE, Grand Rapids, MI 49503
Throughout his research career, Jeremy Van Raamsdonk has trained in eight unique research environments: Dr. Santosh Misra (genetics of plant resistance), Dr. Patrick Dennis (halophilic archaebacteria), Dr. Patricia Chang (gene therapy for hemophilia B), Dr. Peter Lansdorp (telomere biology), Dr. Michael Hayden (Huntington disease), Dr. Nicole Deglon and Dr. Patrick Aebischer (lentiviral gene therapy vectors), Dr. Blair Leavitt (Huntington disease) and Dr. Siegfried Hekimi (genetics of aging). During that time, Dr. Van Raamsdonk developed an expertise in both aging and neurodegenerative disease. In addition, Dr. Van Raamsdonk has experience with two genetic model organisms: C. elegans and mice. Dr. Van Raamsdonk joined the Van Andel Research Institute as an Assistant Professor in 2012 and became an adjunct Assistant Professor in the Department of Translational Science and Molecular Medicine in 2013. While not in the laboratory, Dr. Van Raamsdonk enjoys many sports and outdoors activities, especially at the seaside or up a mountain.
|Institution||Field of Study||Degree||Year|
|University of British Columbia||Biochemistry||B.Sc. (Hons.)||1997|
|McMaster University||Medical Sciences||M.Sc.||1999|
|University of British Columbia||Medical Genetics||Ph.D.||2005|
|McGill University||Biology||Postdoctoral fellow||2006-2012|
Dr. Van Raamsdonk’s laboratory is focused on gaining insight into the aging process and using that information to promote healthy aging and decrease the severity of neurodegenerative disease. The laboratory utilizes a genetic approach using animal models including C. elegans and mice. Research in the laboratory aims to understand the genetics of aging as well as the pathogenesis of Parkinson and Huntington disease. Ultimately the goal of Dr. Van Raamsdonk’s work is to improve human health through a translational model beginning in worms and validating in mice.
- Characterization of C. elegans models of neurodegenerative disease
- C. elegans lifespan assays
- Measurement of physiologic rates in C. elegans
- Assaying stress resistance in C. elegans
- Generating transgenic worm models
- Genetic analysis in C. elegans
- Cognitive and motor behavioral testing in mouse models
- Brain sectioning: cryostat, vibratome
- Western blotting